Fibrillins are large extracellular macromolecules that polymerize to form the backbone structure of connective tissue microfibrils.Mutations in the gene for fibrillin-1 cause the Marfan syndrome, while mutations in the gene for fibrillin-2 cause Congenital Contractural Arachnodactyly.Both are autosomal dominant disorders, and both disorders affect
The paper addresses the problem of transient elastodynamics analysis of a thick-walled, fluid-filled spherical shell embedded in an elastic medium with an analytical approach.This configuration is investigated at first step for a full-space case.Different constitutive relations for the elastic medium, ROSE WATER shell material and filling fluid can
Background: Understanding how the elderly in developing countries spend their time has received little attention.Moreover, the potential of time use data to discern variation in activity patterns has not been fully realized by methods which use a mean added time approach.Objective: To uncover patterns of time use among the elderly (60 years and old